Ampicillin

Indications: urinary-tract infections, otitis media, sinusitis, chronic bronchitis, and gonorrhea.

Cautions: history of allergy; renal impairment; chronic lymphatic leukemia; and possibly HIV infection.

Contra-indications: penicillin hypersensitivity.

Side-effects: nausea, diarrhea; rashes (discontinue treatment); rarely, antibiotic-associated colitis.

Dose: by mouth, 0.25-1 g every 6 hours, at least 30 minutes before food.

Gonorrhea, 2-3.5 g as a single dose with probenecid 1 g.

Urinary-tract infections, 500 mg every 8 hours

By intramuscular injection or intravenous injection or infusion, 500 mg every 4-6 hours; higher doses in meningitis.

Child under 10 years, any route, half adult dose.

TETRACYCLINE

Indications: exacerbations (загострення) of chronic bronchitis; pleural effusions due to malignancy or cirrhosis.

Precautions: hepatic impairment; renal impairment; rarely causes photosensitivity.

Contra-indications: pregnancy and breast-feeding, children under 12 years of age, systemic lupus erythematosus.

Side-effects: nausea, vomiting, diarrhea; headache; hepatoxicity.

Dose: by mouth, 250 mg every 6 hours, increased in severe infections to 500 mg every 6-8 hours.

Non-gonococcal urethritis, 500 mg every 6 hours for 7-14 days.

By intravenous infusion, 500 mg every 12 hours; max. 2 g daily.